Pegylated Mechano Growth Injectable Peptide Hormones Powder
Bodybuilding Peg-Mgf 2mg/vial
PEG MGF Basic Info.
Function: Promotion Development Dosage
Active Substance: It is PEGylated MGF
Application: PEGylation is the act of attaching a Polyethylene
glycol (PEG) structure to another larger molecule (in this case,
(MGF). The PEG acts as a protective coating and the theory here is
that this will allow the MGF to be carried through the blood stream
without being broken down.
PEG MGF Description:
Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth
factor/repair factor that is derived from exercised or damaged
muscle tissue, Its called MGF as IGF-1Ec is a bit of a mouthful and
harder to identify amongst the other igf variants.
What makes MGF special is its unique role in muscle growth.
MGF has the ability to cause wasted tissue to grow and improve
itself by activating muscle stem cells and increasing the
upregulation of protein synthesis, this unique ability can rapidly
improve recovery and speed up muscle growth.
MGF can initiate muscle satellite (stem) cell activation in
addition to its IGF-Ireceptor domain which ithen in turn ncreases
protein synthesis turnover, and therefore can if used correctly
improve muscle mass over time.
The liver produces 2 kinds of MGF splice variants of igf..
1) IGF-1Ec This is the first phase release igf splice variant and
it appears to stimulate satellite cells into activation, This is
the closest variant to synthetic MGF.
2) liver type IGF-IEa this is the secondary release of igf from the
liver, and its far less anabolic.
MGF differs from the second variant IGF-IEa as it has a different
peptide sequence which is responsible for replenishing the
satellite cells in skeletal muscle, in other words it is more
anabolic and longer acting than the systematic release of the
second MGF liver variant.
So just think of MGF as a highly anabolic variant of igf. After you
have trained, the IGF-I gene is spliced towards MGF then that
causes hypertrophy and repair of local muscle damage by activating
the muscle stem cells as well as other important anabolic
processes, including the above mentioned protein synthesis, and
increased nitrogen retention.
In rats some studies have shown muscle mass increases of 20 percent
from a single mgf injection.. somewhow i think many of these
studies are not accurate, however the potential is undeniable.
PEG MGF Usage:
Mechano Factor (MGF) exhibits local effects in skeletal muscle and
without cannot travel through the body without modification. The
problem with synthetic Mechano Factor (MGF) is that it is
introduced intramuscularly and is water based so it goes into the
blood stream. When used this way, Mechano Factor (MGF) only remains
stable in the blood stream for a few minutes. Biologically produced
MGF is made locally and does not enter the bloodstream.
It is also short acting so stability is not an issue. By PEGylating
the Mechano Factor (MGF) it is almost as efficient as local
produced Mechano Factor (MGF) when used intramuscularly. This is
accomplished by surrounding part of the peptide with a structure of
polyethylene glycol, which can be attached to a protein molecule.
The polyethylene glycol groups protect the peptide but do not
surround it completely. The active sites of the peptide are still
free to do their biological function. In this case the shell is a
negative charged shield against positively charged compounds that
would affect the protein
PEG MGF Dosage:
Typical dosage of PEG-MGF is between 200mcg. - 400mcg. per week but
many bodybuilders have said to "research" this peptide at dosages
exceeding 1,500 mcg weekly with no adverse effects.
Because PEG MGF can cause site specific muscle growth, it is
recommended to inject PEG MGF bi-laterally to ensure symmetrical
gains. The most effective test results were experienced in users
injecting the PEG MGF post exercise.
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